Jobs at Bristol Myers Squibb

Lead planning and execution of neuroscience clinical trials as Clinical Trial Lead. Oversee study startup, conduct, and close-out activities; supervise clinical scientists; develop and review protocols, ICFs, CRFs, clinical narratives and CSRs; perform clinical data review, trend identification and query resolution; support site-facing training and cross-functional collaboration; liaise with external partners and contribute to clinical development planning and regulatory documents.

Provides medical accountability and oversight for Phase 1-3 neuroscience clinical trials. Performs medical monitoring, safety assessment, protocol input, site interactions, and medical education. Designs clinical plans with cross-functional teams, leads benefit/risk analysis, supports regulatory and health authority interactions, authors clinical content, and cultivates investigator and thought-leader relationships.

Lead global regulatory strategy for Neuroscience development and marketed products. Serve as primary interface with health authorities, build global regulatory plans, advise cross-functional teams, evaluate regulatory landscape, support due diligence and submissions, and guide regional regulatory staff to align development and commercialization strategies.

Lead clinical development strategy and execution for GI oncology indications. Oversee design, conduct, analysis, and regulatory submission content for clinical trials; manage teams of physicians and scientists; ensure quality, GCP compliance, risk mitigation, and cross-functional engagement with investigators, KOLs, regulators, and senior leadership.

Lead clinical design and execution for neuroscience trials, serving as trial lead or co-lead. Develop protocols/ICFs, data review plans, CRF design, training materials; monitor data trends; contribute clinical text to CSRs and regulatory documents; liaise with KOLs and cross-functional teams; support study governance and submissions.

Operate and troubleshoot automated, high-throughput mammalian antibody expression and purification workflows (4–100 mL), perform QC analytics (A280, CE-SDS, SDS-PAGE, anSEC, endotoxin), integrate liquid handlers and AKTA systems, interface with lab software (Benchling, Geneious), and collaborate with discovery, automation, and AI/ML teams to accelerate antibody discovery.

Lead analytics strategy and execution for a global oncology clinical trial portfolio. Manage and mentor analytics teams, oversee feasibility, enrollment forecasting, and scenario modeling, ensure cross-trial consistency in dashboards and tools, advise TA leadership on trial strategy and cost implications, coordinate field insights and integrate analytics with clinical supply planning, and drive capability building and standards across the TAIP organization.

The Senior Application Engineer will develop cloud-native applications and APIs, focusing on AI products, utilizing AWS technologies, and engaging in Agile project cycles.

Lead design and execution of clinical trial activities for psychiatry programs, potentially serving as Clinical Trial Lead. Develop protocols, ICFs, Data Review Plans; perform literature review, medical writing, data trend monitoring, CRF review, site/CRA training, and contribute clinical content to CSRs and regulatory documents while collaborating with cross-functional and external partners.

Lead and develop a therapeutic-area team of scientific writers, applying advanced regulatory documentation expertise to create content libraries, standardize processes and tools, and drive document automation initiatives. Provide managerial, scientific, and customer-focused leadership to ensure consistent regulatory documentation across development and lifecycle management globally.

Serve as subject-matter expert for multiple QC test methods across products; lead method transfers, validations, CAPAs, investigations, and continuous improvement; author protocols/reports and support regulatory inspections; perform complex troubleshooting, release and stability testing; train and mentor staff; own change controls and contribute to OpEx/CI initiatives while ensuring compliant, safe execution.

Lead global eCOA management for clinical trials, ensuring technology, processes, vendor partnerships, data quality, and regulatory compliance. Deliver eCOA for complex neuroscience rater studies, define metrics, drive improvements and projects, manage bookings and resources, represent function for audits/inspections, and lead and develop a global team.

Lead and execute biomarker and drug development data science efforts: develop computational methods and predictive models for multimodal clinical and omics data, perform high-dimensional statistical analyses, partner with statisticians and translational scientists on protocols and SAPs, validate biomarker assays for trials, implement scalable ML/DL solutions, and manage cross-functional resources to deliver quality results on timelines.

Design and execute translational oncology studies to develop biomarker, pharmacodynamic, and target-engagement assays. Use flow cytometry, multiplexed and quantitative assays (ELISA, MSD, Luminex), functional genomics (CRISPR, RNAi, ORF), and in vitro/ex vivo models to inform clinical decision-making. Independently run experiments, troubleshoot, analyze data, coordinate with project teams and CROs, and co-author study reports and publications.

Lead the Target Sciences team in utilizing statistical genetics to inform drug discovery and drive transformative insights. Oversee cross-biobank analyses, coordinate research efforts, and communicate key findings to stakeholders.

The Principal Scientist will drive AI integration in oncology target discovery, analyze multimodal datasets, and lead cross-functional collaborations to enhance decision-making in drug development.

The Director of Clinical Data Acquisition Strategy will lead the strategy and technology roadmap for acquiring clinical trial data, ensuring optimal site and patient experiences, and integrating automation and AI to enhance data processes.

Senior AI Engineer will design and build cloud-native, agentic AI applications and platform patterns on AWS. Responsibilities include backend services (Python/FastAPI, TypeScript/Node), agent orchestration, retrieval and knowledge architectures, CI/CD and IaC, security and observability, and technical leadership to drive MVPs to production within agile AI Accelerator cycles.

Lead clinical strategy and oversight for early-phase neuroscience programs. Manage matrixed Global Clinical Physicians, design and interpret Phase I and translational studies, drive biomarker development, interact with regulators and KOLs, and ensure GCP/compliance while mentoring teams to advance pipeline assets.

Provide medical accountability and oversight for Phase 1–3 immunology clinical trials, leading medical monitoring, protocol design, safety assessments, regulatory writing, investigator engagement, and cross-functional study delivery while ensuring GCP compliance and contributing to clinical strategy and scientific leadership.