Jobs at AstraZeneca

Lead Biologics AI strategy and execution to integrate advanced ML with wet‑lab discovery. Own cross‑functional programs, develop protein/structure‑aware models, establish closed‑loop design‑build‑test‑learn workflows, set data governance, oversee ML lifecycle and deployment, mentor teams, and represent AstraZeneca externally through publications and collaborations.

Develop and maintain end-to-end MS proteomics analysis pipelines, containerized workflows, and data infrastructure. Design proteomics data models, apply FAIR principles, build searchable result databases, and perform proteomics analyses. Collaborate with chemical biology teams to support study design, quality assessment, scalable analytics, and AI-enabled capabilities while establishing software engineering best practices.

Develop and scale automated translational pathology workflows and Python pipelines; apply deep learning and foundation models to whole-slide image analysis; integrate tissue, preclinical, and clinical data; quantify target engagement and pharmacodynamics; produce visualizations and decision-ready outputs; ensure reproducibility, GxP awareness, and cross-disciplinary collaboration to inform oncology indication and dosing strategies.

Lead competitive intelligence for Oncology R&D by managing a team to deliver clinical and commercial analyses, shape therapy-area strategy, inform senior leadership and investment decisions, and influence cross-functional portfolio choices.

Partner with scientists and product teams to design, prototype, deploy, and scale production-grade cheminformatics and AI-enabled software for drug discovery. Bridge chemistry, data, and engineering to build APIs, data pipelines, containerized services, and platform infrastructure while driving engineering best practices, performance tuning, and user-validated solutions.

Lead U.S. HCP marketing strategy and launch execution for a new HSCT-TMA indication. Develop brand plans, HCP and KOL engagement, market insights, cross-functional alignment, agency and budget management, and monitor launch performance while ensuring regulatory compliance and stakeholder collaboration to drive market shaping and commercial success.

Lead translation of U.S. brand and launch strategy for an IgAN indication into integrated marketing and launch plans. Drive omnichannel programs, disease awareness, field readiness, market-shaping initiatives, cross-functional alignment, metric tracking, agency and budget management, and continuous optimization to ensure successful launch and in-market performance.

Provide high-level administrative support to the SVP and Immunology leadership: manage complex global calendars, plan travel and visas, process expenses and POs, maintain digital repositories, draft executive communications, coordinate meetings and governance, run special projects, and liaise across matrixed functions to ensure smooth execution of R&D priorities.

Manage design, administration, and analysis of field-based sales incentive programs for US commercial teams. Partner with technology to automate reporting and calculations, ensure data accuracy, respond to field inquiries, generate insights, and ensure compliance with company processes.

Lead AstraZeneca's Boston corporate affairs and communications strategy to strengthen reputation, stakeholder relationships, and community engagement. Develop and deliver integrated communications plans across media, events, digital, government affairs and internal channels; manage reputational risk and crisis response; coach senior leaders; coordinate cross-functional teams to maximize impact; measure outcomes and amplify AZ science and STEM initiatives within the Boston ecosystem.

Lead and manage a country clinical operations team accountable for study execution, quality, timelines, resource optimization, vendor oversight, KPI monitoring, cross‑functional collaboration, inspection readiness, site selection/start‑up/enrollment/data deliverables, and continuous improvement across multiple global clinical trials.

Lead clinical scientific strategy and execution for a respiratory product across development, regulatory submissions, benefit-risk assessment, and labeling. Serve as single clinical/scientific contact for R&D and therapeutic-area leaders, ensure timely delivery of clinical studies and submission components, mentor physicians/scientists, and partner with global commercial and regulatory stakeholders to support product value and reimbursement.

Perform early-discovery research at the intersection of gene delivery and cell therapy: engineer cell lines and primary immune cells via viral and non-viral methods; develop high-throughput in vitro functional assays (flow cytometry, plate reader, ELISA/MSD, qPCR); execute and analyze immune functional assays (cytotoxicity, co-cultures, proliferation, cytokines); interpret and present experimental data to stakeholders.

Lead AstraZenecas enterprise AI strategy for Discovery to embed multimodal AI, mechanistic modeling, and foundation models across target identification, compound optimization, and early decision-making. Partner with Discovery Biology, Chemistry, Translational Medicine and Therapeutic Area leaders to translate scientific priorities into reusable AI capabilities. Build and run a global team (~20 direct/indirect reports), manage external partnerships, and drive adoption and scaling of AI-enabled discovery across the organization.

Lead cross-functional Global Product Team for late-stage weight management assets, define development and commercial strategies, manage risks and IP, deliver Target Product Profiles and business cases, ensure governance and compliance, drive team performance, and engage executive leadership to maximize portfolio value.

Lead global Early Oncology clinical operations strategy and execution, integrating AI and digital tools, managing cross-functional teams and vendors, ensuring regulatory compliance, and driving operational excellence, resource optimization, and talent development across the EO portfolio.

Lead and scale a centralized AI organization for Cell Therapy Discovery and Targeted Immune Engagers: define AI strategy, prioritize and deliver initiatives (agentic knowledge hubs, predictive CAR-T models, in silico protein/binder design, CRISPR off-target workflows), embed AI across R&D, automate workflows, build multi-site teams, ensure governance/compliance, drive KPIs and executive communication, and upskill scientific teams.

Lead enterprise deal analytics for US market access: build pre-deal models and assumptions, create scalable frameworks, design pull-through measurement, execute post-deal value realization, and partner with Contracting, Pricing, Finance and Legal to inform negotiations and executive decisions that drive access and commercial performance.

Lead US commercial strategy and launch planning for a rare disease portfolio. Drive annual and multi-year planning, coordinate cross-functional launch execution, create KPIs and dashboards, manage Smartsheet launch tools and training, represent Business Strategy in senior forums, and build scalable operating models and governance to accelerate product launches.

Design, execute, optimize, and troubleshoot in vitro cell-based assays to assess interventions on cellular aging and signaling pathways. Support ex vivo work complementary to CRO in vivo studies, analyze and present preclinical data, collaborate with project teams, and stay current with aging research and technologies.