Jobs at AstraZeneca

Lead integrated bioanalytical strategy for Oncology programs, designing and implementing PK, immunogenicity and biomarker assays. Provide scientific oversight of internal labs and CROs, manage assay transfer/validation, interpret complex datasets, contribute to regulatory submissions, represent IBA externally, publish scientific work, and prioritize resources across concurrent projects to support clinical development.

Lead and oversee late-phase respiratory and immunology clinical programs (Phase IIb-IV), managing global study strategy, design, safety surveillance, regulatory interactions, publication strategy, and a team of study physicians/scientists to deliver approval-supporting data and meet global regulatory and label objectives.

Lead enterprise statistical programming strategy across Quantitative Sciences; drive AI/automation and CDISC-compliant, submission-ready outputs; oversee people, budgets, statistical computing environments, CRO governance, capacity planning, and regulatory/payer submission readiness while delivering continuous improvement.

Lead financial and scientific evaluations of M&A, licensing, and commercialization opportunities in biopharma. Manage transaction processes, due diligence, valuations, and deal structuring with cross-functional teams. Prepare financial models, deal analyses, and materials for senior leadership; support negotiations, closings, and ad hoc corporate development projects.

Lead global clinical development strategy and execution for hematology/oncology programs (primarily CLL), overseeing clinical plans, regulatory submissions, cross-functional teams, timelines, budgets, and governance to deliver proof-of-concept through late-stage development.

Lead translation of U.S. brand and launch strategy for an IgAN indication into integrated marketing and launch plans. Drive omnichannel programs, disease awareness, field readiness, market-shaping initiatives, cross-functional alignment, metric tracking, agency and budget management, and continuous optimization to ensure successful launch and in-market performance.

Lead epidemiology strategy across therapeutic areas, design and oversee observational and real-world evidence studies, provide technical expertise in pharmacoepidemiology, manage and mentor epidemiology teams, collaborate with cross-functional stakeholders (Clinical Development, Safety, Regulatory, HEOR), publish scientific findings, and represent the company externally. Ensure high-quality deliverables, optimize resources, and drive methodological innovation.

Lead US omni-channel HCP and patient marketing for aHUS/TMA: develop and execute digital and multichannel campaigns, set KPIs, manage agencies and budgets, support speaker bureau and professional society assets, and collaborate cross-functionally to drive HCP and patient engagement.

Lead and execute oncology R&D transactions including licensing, acquisitions, collaborations and divestments. Build external networks, negotiate deals, coordinate cross-functional partners, transition post-deal to alliance management, report to senior management, and improve processes using emerging technologies.

Lead global clinical development for Amyloidosis & Rare Cardiology programs across all stages, defining strategy, designing and overseeing trials, managing regulatory interactions (IND/IMPD, BLA/NDA/MAA), guiding cross-functional teams, supporting business development, and driving programs to registration.

Lead US advertising and promotional regulatory review for assigned products, serve as RA liaison with FDA/OPDP/APLB, develop/adopt review processes and SOPs, advise cross-functional teams, provide training, mentor colleagues, and ensure promotional compliance with FDA regulations and global standards.

Lead development of analytical methods, formulations and drug delivery systems for small-molecule projects. Serve as pharmaceutical expert on global project teams, design and run experiments, evaluate data, and present recommendations. Develop novel formulations and enabling technologies, collaborate cross-functionally with chemists and biologists, and align scientific strategy to business needs.

Lead global labeling strategy for respiratory and immunology products across development and lifecycle. Direct preparation of Core Product Information and US/EU prescribing information, negotiate with health authorities, guide study design and evidence generation, steward labeling policies/SOPs and GxP compliance, build labeling team capability, and support portfolio planning and governance to secure advantageous product labeling.

Provide strategic leadership for statistical programming in early oncology, managing programmers delivering phase 1/2 trials. Ensure high-quality, compliant deliverables (CDISC, 21 CFR), drive automation and process improvements, oversee resourcing, budgets and cross-functional collaboration, and support regulatory submissions.

Lead design and implementation of bioanalytical strategies for oncology programs, overseeing PK, immunogenicity, and biomarker assays. Serve as IBA project lead, coordinate with internal teams and CROs, ensure assay development/validation, provide scientific oversight, support regulatory submissions, mentor staff, and represent IBA externally through presentations and publications.

Lead Quality oversight for external manufacturing partners (CDMOs/CMOs), testing labs and suppliers for radiopharmaceuticals. Ensure cGxP compliance, manage audits/inspections, risk assessments, investigations/CAPA, technology transfers, and quality governance while partnering cross-functionally to secure supply and continuous improvement.

Provide biostatistical expertise for complex clinical study design, modelling and simulation, develop statistical analysis plans, perform analyses for regulatory submissions and publications, coach junior statisticians, and improve methodology, quality and delivery across projects.

Lead development and delivery of Respiratory therapeutic-area strategy and portfolio prioritization, integrate clinical and translational plans across assets, lead cross-functional Respiratory Council, provide strategic counsel to senior leaders, and drive competitive intelligence and above-asset initiatives.

Lead clinical and scientific strategy for obesity/diabetes assets as the senior medical authority. Accountable for clinical study design, delivery, benefit/risk assessment, TPP/TPC/CDP strategy, regulatory interactions, and cross-functional stakeholder alignment to ensure ethical, compliant, and timely program execution.

Lead external R&D and early pipeline communications to position AstraZeneca as a science-led organization. Develop integrated global campaigns across digital, social and traditional media; craft disease and asset narratives; produce press materials; advise and coach R&D leaders; support media, investor and partner communications; manage crisis preparedness; build patient and market engagement programs; measure and evaluate communications impact.