Jobs at AstraZeneca PLC

Conduct immunology research supporting drug discovery for autoimmune diseases. Characterize immune pathways, develop and validate cellular, molecular, and protein assays, analyze complex datasets, and generate translational data using human primary and disease tissue-derived cells. Collaborate cross-functionally, contribute to therapeutic strategy, maintain rigorous laboratory records, and publish research findings.

Leads global patient safety activities for assigned pharmaceutical products, including safety data analysis, signal surveillance, aggregate safety reporting, risk management plans, regulatory submissions, health authority responses, and safety governance. Partners with medical directors and cross-functional teams, authors clinical and regulatory documents, supports risk-benefit assessments, trains junior staff, and drives process improvements while ensuring compliance with global pharmacovigilance regulations.

Leads the application of agentic AI, predictive models, and biological foundation models to identify and validate novel drug targets. Partners with therapeutic-area scientists, deploys multi-agent systems, advises cross-functional teams, contributes to predictive modeling strategy, and advances target prioritization across AstraZeneca’s R&D organization. The role also requires scientific leadership through publications, presentations, collaborations, and technical influence across organizational boundaries.

Leads oncology bioanalytical strategy and delivery across PK, PD, immunogenicity, biomarkers, and multiple therapeutic modalities. Oversees assay design, development, validation, CRO execution, data interpretation, regulatory submissions, and health authority interactions. Serves as project lead and scientific subject matter expert, partnering with cross-functional teams and external laboratories. Provides scientific oversight, manages stakeholders and resources, mentors bioanalytical leaders, and contributes to publications, presentations, and strategic initiatives.

Own the strategy, roadmap, governance, and value realization for AstraZeneca’s clinical AI portfolio. Prioritize initiatives across Phases I–III and clinical operations, build business cases, assess build-buy-partner options, and translate emerging AI capabilities into actionable plans. Partner with clinical, research, technical, regulatory, and executive stakeholders to turn clinical questions into funded AI programs, establish operating models, and drive adoption and measurable impact across the enterprise.

Leads AstraZeneca’s clinical AI research agenda, directing AI/ML methodology for clinical development from Phase I through Phase III. Responsibilities include managing researchers, developing multimodal and predictive models, establishing evaluation and methodological standards, translating research into regulated environments, collaborating with clinical and regulatory teams, engaging external scientific bodies, and building a high-performing research organization.

Leads global late-phase oncology clinical development, translating strategy into protocols, overseeing trial delivery, recruitment, medical monitoring, data interpretation, regulatory submissions, and registration activities. Partners with physicians, clinical operations, regulatory, commercial, and external stakeholders to guide pivotal studies and governance decisions. The role also supports investigator engagement, training, process improvement, mentoring, and potentially line management.