Jobs at Beam Therapeutics

Lead pharmacovigilance activities for Beam products, providing scientific and operational PV support across clinical development and lifecycle. Oversee safety monitoring, ICSR assessment, signal detection, aggregate reporting, vendor management, inspection readiness, SOP development, cross-functional safety governance, database migrations, and PV training. Act as PV SME and contribute to PV strategy, quality, and compliance.

Lead study-level biostatistics for clinical trials: design, SAPs, TLFs, CRF and randomization review; oversee CRO biometrics and programmers; perform analyses, support regulatory submissions, and collaborate cross-functionally.

Lead Beam's metabolic clinical development as medical head for base-editing gene therapies. Set strategy, design clinical plans, oversee trial execution and patient safety, interact with regulators, support R&D and business development, and manage/mentor physician and clinical scientist teams.

The role leads global supply chain planning, ensuring uninterrupted supply of products, inventory management, and effective collaboration with cross-functional teams.

The Vice President, Compliance oversees the Corporate Compliance Program, ensuring regulatory adherence, managing clinical supplies, and fostering a culture of accountability.

Lead state government affairs strategy to influence legislators, governors, and state Medicaid officials; build state-level networks; coordinate lobbying and advocacy; advise on federal/state policy risks and opportunities; collaborate with market access, regulatory, and patient advocacy teams; travel as needed.

Support monthly close, prepare journal entries and reconciliations, assist with internal/external financial statements, support audits and SOX reviews, contribute to system implementations and ad hoc financial analyses.

Lead the Project Management function and manage the BEAM-302 program, aligning cross-functional teams on strategy, timelines, budgets, risks, and deliverables. Oversee portfolio integration, governance support, scenario planning, risk mitigation, and operational excellence initiatives. Drive adoption of best practices and AI/tools to improve consistency and execution, and communicate program status to leadership and stakeholders.

Lead CMC strategy and execution for in‑vivo and ex‑vivo programs from IND through BLA. Oversee process and analytical development, manufacturing scale‑up, regulatory CMC submissions (Module 3), risk management, cross‑functional teams, CDMO oversight, and ensure cGMP/ICH compliant product lifecycle strategies.

Support and execute investor relations strategy; coordinate investor outreach and meetings; track investor sentiment and ownership trends; prepare earnings materials, scripts, decks, and disclosures; translate scientific and clinical updates into investor-ready messaging; manage consensus models, investor website updates, and cross-functional communications with R&D, Clinical, Regulatory, Finance, Legal, and Commercial teams.

Lead sponsor-side clinical data management for assigned studies from start-up through database lock. Oversee CRO/vendor data activities, ensure CDASH/CDISC/SDTM-compliant CRF and database design, manage edit checks, reconciliations, query resolution, and inspection-ready documentation. Track metrics, mitigate risks, and collaborate with Clinical Ops, Biostatistics, Medical, Regulatory, and Quality to support study objectives and regulatory submissions.

The Associate Director/Director of Toxicology leads nonclinical safety assessments, oversees study execution, and supports regulatory filings for gene therapy programs.